wanted from 01.08.2026 at the Department of Cardiology, Heidelberg.

The research group of Dr. Manju Kumari from the Department of Cardiology is seeking talented and motivated researchers to work as a PhD student on a DFG-funded grant. The project is part of CRC1550 focusing on studying ‘Cardiocrine signaling in immune-metabolic communication’. We have recently shown that interferon signaling plays a critical role in regulating cardiac immunometabolism during myocardial infarction. However, the effect of cardiocrine signaling in these processes remains unclear. This project aims to unravel the role of interferon signaling in the progression of cardiocrine signals to cardiac fibrosis. Utilizing excellent transgenic mouse models, hiPSC-derived cardiomyocytes in combination with computational approaches for big data analysis, we will investigate the cardiac immunometabolic network regulating cardiac fibrosis. Additionally, the candidate will have the opportunity to apply for grants supporting further research work to enhance career prospects. The candidate will be working in a diverse interdisciplinary team and thus ability to work independently, troubleshooting and multitasking skills, and capability of intellectual input for project development are preferred. Applicants should submit a motivation letter, two reference letters or contact details of the referees, CV, and publication list. 

• Job-ID: V000015706
• Field of application: Klinik für Kardiologie, Angiologie und Pneumologie
• Location: Heidelberg
• Job Category: Science and teaching
• Working hours: Part time (65 %)
• Published: 01.07.2026
• Limitation:Temporary (4 years)
• Contract:TV-L

Your Tasks

• To determine cell-type specific alterations in the transcriptome induced by interferon signaling
• To investigate the effect of loss-of-function of regulatory factors in controlling cardiac immunometabolism using transgenic mouse models
• To unravel the intercellular communication in healthy vs. diseased heart in mice and human models
• To utilize computational modeling and integrate single-cell multi-omics data
• To coordinate research projects with other members in the group

Your Profile

• Master degree in Molecular Biology/Biochemistry/Cell Biology/Life Sciences/ related subjects
• Candidate must have experience in molecular cell biology techniques (cloning, transfection, qPCR, IHC, IP, IF etc.)
• Candidate must be willing and comfortable working with mouse models and gaining experience on experimental rodent models of heart failure, inflammation and obesity is essential
• Experience in cell culture- immortalized or primary is essential
• Excellent communication and organizational skills with excellent knowledge of written and spoken English

We offer

• Goal-oriented, individual training and development opportunities (e.g. Learn and perform sc and sn-RNA seq and data-analysis)
• Working with the latest techniques/technical equipment: echocardiography, confocal microscopy, flow cytometry, in vitro mutagenesis 
• Possibility of doctorate 
• Possibility to publish scientifically is offered and supported
• Regular team meetings
• Interdisciplinary cooperation 
• Collectively agreed remuneration according to TV-L E13, attractive company pension scheme (VBL)
• 30 days vacation
• Sustainable travel: job ticket
• Family-friendly working environment: cooperative arrangements for childcare, subsidy for child vacation care, advice for employees with relatives in need of care
• Wide range of health, prevention and sports offers

Contact & Application

For further information please contact Manju Kumari via e-mail or phone.

Interested?

Applications will be accepted until 25.06.2026 directly online.

Klinik für Kardiologie, Angiologie und Pneumologie Manju Kumari, Junior Group Leader Im Neuenheimer Feld 410 69120 Heidelberg +49-6221-56-310561manju.kumari@med.uni-heidelberg.de

Note: The UKHD is subject to the provisions of the Infektionsschutzgesetz. Therefore, a valid measles immunity certificate is required for all persons employed at the UKHD.

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